Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Contemporary Mexican Restaurants in Medical Center

Price
Regions
Neighborhoods
Dining Options
Seating Options
Accessibility

2 restaurants available nearby

A photo of Ácenar restaurant
4.5
Awesome(2597)
Price: Moderate
• Contemporary mexican • Downtown
Booked 13 times today
Ácenar, nestled in the vibrant heart of Downtown San Antonio, offers a unique and invigorating fusion of Texas regional and Mexican cuisines. This contemporary culinary gem, helmed by the renowned restaurateurs Lisa Wong and Pete Selig, presents an eclectic menu that dazzles with its bold Latin-infused flavors. Executive Chef Richard Sánchez masterfully crafts dishes like the seafood enchiladas and San Antonio style enchiladas, which are consistently lauded for their authenticity and innovation. Diners rave about the "amazing" Tres Leches cake and the "incredible" mole enchiladas, highlighting the restaurant's commitment to quality and creativity. With its prime river walk location and a modern, stylish setting, Ácenar is a standout destination for those seeking a sublime fusion dining experience.
A photo of Ostra at Mokara Hotel & Spa restaurant
4.7
Exceptional(1315)
Price: Moderate
• Contemporary mexican • Downtown
Booked 10 times today
Nestled along the vibrant River Walk in downtown San Antonio, Ostra at Mokara Hotel & Spa stands out as a gem of Contemporary Mexican cuisine. Diners are consistently impressed, describing their experiences as “spectacular” with “exceptional service” and a menu that “delights” with its creativity and finesse. The restaurant takes pride in sourcing fresh and organic ingredients, ensuring each dish, from the tantalizing calamari to the perfectly cooked halibut, is of the highest quality. Renowned for their innovative dishes and an extensive selection of tequilas, Ostra provides an ambiance that’s both relaxed and contemporary. Whether it’s the riverfront terrace dining or the dramatic oyster bar, Ostra offers a memorable dining experience right in the heart of San Antonio.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

Explore OpenTable

  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo