Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Seafood Restaurants in Medical Center

Price
Regions
Neighborhoods
Top Rated
Dining Options
Seating Options
Accessibility

28 restaurants available nearby

A photo of Myron's at Alon Town Center restaurant
1. Myron's at Alon Town Center
4.9
Exceptional(4639)
Price: Expensive
• Seafood • North San Antonio
Booked 19 times today
Myron’s Prime Steak House in North San Antonio is a culinary gem renowned for its exceptional seafood offerings. Nestled in the Alon Towne Centre, Myron’s delights seafood enthusiasts with dishes that consistently exceed expectations. Patrons rave about the freshness and quality of the seafood, with reviews highlighting the "perfectly cooked" sea bass and "outstanding" grilled shrimp. The restaurant's commitment to excellence is evident, as one diner praised, "Always a great place to get fresh meat and seafood and great service." Myron’s not only promises a delightful dining atmosphere but also ensures each seafood dish is crafted to perfection, making every visit memorable.
A photo of Red Lobster - San Antonio - NW Loop 410 restaurant
2. Red Lobster - San Antonio - NW Loop 410
4.4
Awesome(15)
Price: Moderate
• Seafood • North San Antonio
Elevate your day at Red Lobster, where fun meets fancy and every meal is a celebration. Whether you’re marking a special occasion or treating yourself or your crew, Red Lobster is the perfect place to enjoy all your seafood favorites. Dive into our signature shrimp, wild caught lobster and crab, and more. Plus, a variety of fish and popular non-seafood items like our Cajun Chicken Linguini Alfredo. Looking for a showstopper? Create Your Own Ultimate Feast or select a Live Maine Lobster straight from the tank. Or explore our Daily Deals with a different special available each weekday at a price you’ll love. Toast the day with Signature Cocktails including Lobster Punch and Main Deck Margarita Flights to make any moment feel festive. You won’t want to miss our newest menu items or special promotions like Lobsterfest and Crabfest. Reserve online today. Group Dining, To Go, or Catering options. For parties of 11+, please call.
A photo of Chart House Restaurant - Tower of the Americas restaurant
3. Chart House Restaurant - Tower of the Americas
4.5
Awesome(16489)
Price: Moderate
• Seafood • Downtown
Booked 196 times today
Dine in the heart of Downtown San Antonio at Chart House Restaurant, a haven of American cuisine that promises more than just a meal. Celebrated for both its culinary prowess and enchanting views, Chart House offers an array of finely-crafted American dishes, from fresh fish specialties to the sumptuous slow-roasted prime rib. Guests rave about the "delicious food and great service," with highlights including the "best key lime pie ever" and an original Hot Chocolate Lava Cake that perfectly concludes a memorable dining experience. Whether it's the stunning city vistas or the "exceptional service," Chart House provides a dining experience that consistently delights and surprises, making it a must-visit for locals and tourists alike.
A photo of Perry's Steakhouse & Grille - San Antonio restaurant
4. Perry's Steakhouse & Grille - San Antonio
4.8
Exceptional(9258)
Price: Expensive
• Seafood • La Cantera
Booked 82 times today
Perry's Steakhouse & Grille in San Antonio's La Cantera neighborhood is a beacon of American cuisine, offering a genuine taste of culinary excellence. Known for its iconic, "Texas-sized" pork chops and an array of well-crafted dishes, Perry's provides a dining experience that leaves patrons raving about its quality and authenticity. As one diner exclaims, the pork chops are "always amazing," and another recommends not missing the Friday lunch special for a fulfilling experience. The ambiance, including views from Bar 79® and the attentive service, complements the delicious offerings, making Perry's a must-visit for those seeking the heart and soul of American dining in The River City.
A photo of Dean's Steak & Seafood restaurant
5. Dean's Steak & Seafood
4.6
Exceptional(161)
Price: Very Expensive
• Seafood • Downtown
Booked 33 times today
At Dean's Steak & Seafood in Downtown San Antonio, the steak experience is truly unparalleled. Nestled in a historic 19th-century schoolhouse, Dean's offers a selection of prime steaks, including A5 Japanese and Texas Wagyu, celebrated for their succulent and flavorful qualities. Patrons rave about the authenticity and quality of the offerings, with one diner describing their Wagyu as "delicious and fun at the same time," and steaks that were "cooked perfectly" and "tender and flavorful." Whether you're a local or visiting, Dean's is the go-to destination for steak aficionados seeking a top-tier dining experience in a unique, atmospheric setting.
A photo of Bohanan's Prime Steaks and Seafood restaurant
6. Bohanan's Prime Steaks and Seafood
4.8
Exceptional(8220)
Price: Very Expensive
• Seafood • Downtown
Booked 58 times today
Bohanan's Prime Steaks and Seafood in downtown San Antonio is a gastronomic landmark where the allure of tender, prime beef and fresh seafood create a perfect dining experience. Known for its mesquite-grilled steaks like the "spectacular" Akaushi beef, Bohanan’s also boasts a AAA Four Diamond rating and a Wine Spectator’s Best of Award of Excellence. Diners rave about the "perfect steak doneness" and "spectacular table-side desserts flambé." The ambiance, set in a historic building near the River Walk, adds to its charm, making every visit memorable. It’s no wonder guests say, "Bohanan’s is consistently the best service in the city," making it a must-visit for anyone seeking the quintessential steakhouse experience.
A photo of Eddie V’s – Wildfish – San Antonio restaurant
7. Eddie V’s – Wildfish – San Antonio
4.8
Exceptional(6613)
Price: Very Expensive
• Seafood • North San Antonio
Booked 61 times today
Eddie V’s – Wildfish in North San Antonio is a beacon of Steakhouse cuisine excellence, consistently delivering "top-notch" dining experiences. This luxurious destination is renowned for its "critically acclaimed prime center-cut steaks broiled to perfection," making every meal a carnivorous delight. Diners rave about the quality, with reviews highlighting that the steaks are "always cooked to perfection." The ambiance, service, and attention to detail, such as "roses and a card awaited us at the table," elevate each visit, making Eddie V's the go-to spot for special occasions. Whether you're celebrating a milestone or seeking a superb steak dinner, Eddie V's promises an "exquisite dining experience" that's simply unmatched in San Antonio.
A photo of Seasons 52 - San Antonio restaurant
8. Seasons 52 - San Antonio
4.8
Exceptional(671)
Price: Expensive
• Seafood • Alamo Heights
Booked 44 times today
Seasons 52 in Alamo Heights, San Antonio, epitomizes the essence of American cuisine with its ever-evolving seasonal menu that captures the freshness and vibrancy of local ingredients. Praised for its "exceptional food and service," this gem offers dishes that are oak-fire grilled or brick oven roasted, highlighting the natural flavors without the need for a fryer. The ambiance complements the quality of the meals, with guests celebrating everything from casual dining to special occasions, consistently noting the "great food and friendly service, as always!" Whether it's the cedar plank salmon or the innovative wine list, Seasons 52 delivers a top-notch American dining experience, making every visit memorable.
A photo of BLÜ Prime Steakhouse restaurant
9. BLÜ Prime Steakhouse
4.7
Exceptional(588)
Price: Very Expensive
• Seafood • North Central
Booked 21 times today
BLÜ Prime Steakhouse in North Central, San Antonio, is a beacon of culinary excellence, particularly noted for its transformative steak cuisine. Diners consistently rave about the "outstanding flavorful food" and the "exceptional taste ribeye." What sets BLÜ apart is its in-house dry age steak program, ensuring each cut is perfectly aged for peak flavor and tenderness. One patron highlighted, "The steak was one of the most tender and flavorful filets I’ve ever had." The restaurant's commitment to quality is unmatched, with a five-star wine list and a craft cocktail bar to complement your meal. BLÜ Prime Steakhouse is not just a meal; it’s a prestigious dining experience where each steak served is a masterpiece of culinary craft.
A photo of Ruth's Chris Steak House - San Antonio (Airport) restaurant
10. Ruth's Chris Steak House - San Antonio (Airport)
4.8
Exceptional(1878)
Price: Very Expensive
• Seafood • Alamo Heights
Booked 34 times today
Ruth's Chris Steak House in Alamo Heights, San Antonio, epitomizes the pinnacle of Steakhouse cuisine. Celebrating its 30th anniversary, this esteemed restaurant is renowned for its meticulous selection of USDA Prime beef, aged and hand-cut right in the kitchen. Each steak is seared at an intense 1800 degrees Fahrenheit, ensuring a perfect crust that locks in succulent flavors and juices, served sizzling to your table. Diners consistently rave about the "fantastic filets perfectly cooked" and the "ribeye that was over the moon." The exceptional service complements the culinary excellence, with guests frequently praising the attentive and professional staff, making every dining experience memorable. Whether it's for a special occasion or a delightful dinner, Ruth's Chris at San Antonio Airport promises an unmatched steak experience.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you

Explore OpenTable

Discover
OpenTable
  • About Us
  • Blog
  • Careers
  • Press
More
Our sites
Businesses
  • Delight more diners
  • Open for Business Blog
Join us on
  • Privacy Policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable, Inc. 1 Montgomery St Ste 500, San Francisco CA 94104 - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo