Best Southern American Restaurants in Buffalo

19 restaurants available nearby

A photo of BUFFALO CHOPHOUSE - PRIME STEAKS & FRESH SEAFOOD restaurant

1. BUFFALO CHOPHOUSE - PRIME STEAKS & FRESH SEAFOOD

4.8

Exceptional(3345)

Price: Very Expensive

• Southern american • Buffalo

Booked 28 times today

At Buffalo Chophouse in the heart of Buffalo’s Theater District, the steak cuisine is nothing short of legendary. Celebrated as Western New York's premier steakhouse, this establishment serves only the finest USDA Prime steaks, earning rave reviews for their exceptional quality. Diners consistently praise the "buttery" texture of the steaks and the flawless cooking that enhances the rich, natural flavors. The Delmonico steak, paired perfectly with Bearnaise sauce, is a standout, described by a guest as "cooked to perfection." With its upscale yet welcoming ambiance, Buffalo Chophouse remains a top choice for steak lovers, providing a "fabulous dining experience" that guests eagerly anticipate returning to. The consistent excellence in both food and service makes every visit memorable, cementing its reputation as the home of the best steak in Western New York.

2. Patina 250

4.6

Exceptional(1534)

Price: Expensive

• Southern american • Buffalo

Booked 31 times today

Patina 250 in Buffalo, NY, stands as a beacon of Contemporary American cuisine, celebrated for its innovative use of fresh, locally-sourced ingredients that capture the essence of Western New York. Diners rave about the "terrific" food and drinks, highlighting dishes like the "tender and tasty" Filet Mignon and the "amazing" Buffalo Cauliflower. The restaurant’s chic, art-infused decor complements the culinary experience, making it not just a meal, but a vibrant dining event. With accolades like "the best crab cake in Buffalo" and "delicious anniversary dinner," Patina 250 consistently delivers a top-notch dining experience, earning it glowing recommendations for anyone looking for authentic and sophisticated American fare in Buffalo.

A photo of Bacchus Wine Bar & Restaurant restaurant

3. Bacchus Wine Bar & Restaurant

4.7

Exceptional(2783)

Price: Expensive

• Southern american • Buffalo

Booked 16 times today

Bacchus wine bar and restaurant is located in the historic Calumet building in the heart of Buffalo's entertainment district. A seasonal menu highlights the best available ingredients from local and regional farms. Together with our Wine Spectator award winning wine list, this elegant yet casual restaurant has continually been ranked as one of Buffalo's best.

4. 42N at The Flats

4.5

Awesome(33)

Price: Moderate

• Southern american • Buffalo

Booked 6 times today

Discover the culinary charm of 42N at The Flats, a gem nestled in Buffalo's vibrant theater district. This bistro shines with its artisan fare from Queen City Bistro, emphasizing creative and contemporary dishes that perfectly pair with their craft beers and crafted cocktails. Patrons rave about the quality, with one guest highlighting, "Awesome food that compliments the best local beer around." Another diner recommended the "pretzel hamburger," describing it as delicious. Whether it's for a pre-theater dinner or a casual drink, 42N at The Flats offers an "outstanding experience" with its "great food & drinks!" as enthusiastically noted by satisfied customers.

5. w xyz bar

3.8

Excellent(5)

Price: Moderate

• Southern american • Buffalo

Mingle over cocktails at W XYZ® bar. The fun flows freely at this downtown Buffalo gathering spot, located in the Aloft Buffalo Downtown, with everything from pints to Pinot Noirs to specialty sippers, plus a snack-attack menu, mood music and can't-miss events at our 500 Pearl property!

6. Johnny D's

4.3

Awesome(59)

Price: Expensive

• Southern american • Buffalo

Booked 9 times today

Johnny D's in Buffalo offers a quintessential American dining experience that is both authentic and exceptional. Nestled in the Hyatt Regency Buffalo, it's a celebrated spot where the spirit of American cuisine comes to life. Guests rave about the "delicious food" and the "superb steaks," highlighting dishes like the "exceptional" Aged New York Strip. The atmosphere is enhanced by live piano music, adding an elegant touch to the dining experience. Reviewers consistently praise the friendly and professional service, with one noting, "The service was impeccable... and the food was exquisite!" Whether you're a local or just passing through, Johnny D's promises a memorable culinary journey with every visit.

7. Panorama On Seven

4.6

Exceptional(890)

Price: Expensive

• Southern american • Buffalo

Booked 19 times today

Our guests and employees safety and health is our number one priority. We have implemented safety and health guidelines and procedures to do our part and Stop the Spread.Hand-sanitizing stations have been installed throughout our hotel.We have converted our menus to digital menu with QR code. To access our digital menus, guest can scan the QR code with their cell phone camera. Complimentary disposable masks will be available for any guest.All associates have completed a comprehensive Safety and Service Training Program. 716 852 0049

8. Patrick's Rooftop

4.1

Excellent(181)

Price: Moderate

• Southern american • Buffalo

Booked 1 time today

Patrick's Rooftop is Downtown Buffalo's Highest Rooftop Bar and Patio

9. Jack Rabbit

4.6

Exceptional(405)

Price: Moderate

• Southern american • Buffalo

Booked 5 times today

Jack Rabbit in Buffalo stands out as a premier destination for Bar / Lounge / Bottle Service, offering a vibrant atmosphere and a top-notch drink selection. Patrons rave about the "excellent service and drinks," with special mentions of its innovative cocktail mixology and quality draft brews. The bar's ambiance is further enhanced by live music, making it "one of the best in town." Customers consistently praise the friendly and welcoming staff, making everyone feel like a local. Whether you're looking for a lively brunch scene with delicious mimosas or a relaxed evening with expertly mixed drinks, Jack Rabbit promises an unforgettable experience in the heart of Buffalo.

A photo of Southern Tier Brewery Buffalo restaurant

10. Southern Tier Brewery Buffalo

4.4

Awesome(20)

Price: Moderate

• Southern american • Buffalo

Booked 5 times today

Southern Tier Brewery Buffalo is a gem for those seeking authentic American cuisine in Buffalo. Known for its "brewery inspired fare," Executive Chef Frank Johnson masterfully combines classic comfort with a delightful twist. Patrons rave about dishes like the "best chicken sandwich" and "delicious fish tacos," complemented by an array of exclusive brews. The atmosphere is perfect for any occasion, from game days with "the largest TV in the city" to a relaxing Brewer's Brunch. Reviews consistently highlight the welcoming staff and vibrant vibe, making it a must-visit for both locals and visitors. As one diner put it, "Great environment, great food, great selection of beverages and the service was top notch!" Southern Tier Brewery Buffalo truly stands out as a top destination for outstanding American dining and brewing in Buffalo.

‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

Explore OpenTable

Buffalo

Southern american

Best Southern American Restaurants in Buffalo

Price

Regions

Neighborhoods

Top Rated

Dining Options

Seating Options

Accessibility

19 restaurants available nearby

1. BUFFALO CHOPHOUSE - PRIME STEAKS & FRESH SEAFOOD

2. Patina 250

3. Bacchus Wine Bar & Restaurant

4. 42N at The Flats

5. w xyz bar

6. Johnny D's

7. Panorama On Seven

8. Patrick's Rooftop

9. Jack Rabbit

10. Southern Tier Brewery Buffalo

Explore OpenTable