Best Southern American Restaurants in Tenderloin

148 restaurants available nearby

A photo of Biscuits and Blues restaurant

1. Biscuits and Blues

4.7

Exceptional(2013)

Price: Expensive

• Southern american • Downtown / Union Square

Booked 4 times today

Biscuits and Blues in San Francisco's vibrant Theater District offers a unique blend of authentic Southern, Creole, and Cajun cuisine paired with world-class blues music. This celebrated venue, praised for its "excellent night" of entertainment and dining, is a must-visit for both locals and tourists. Patrons rave about the "amazing" Southern Fried Chicken and biscuits and the "melt-in-your-mouth" beef brisket, highlighting the quality and authenticity of the dishes. With its intimate setting and top-notch service, it's no wonder guests say, "If you like R&B, Soul and Blues music plus southern cooking, you need to go here right away!" Biscuits and Blues truly stands out as a gem in San Francisco’s culinary and cultural scene.

A photo of Jasper's Corner Tap and Kitchen restaurant

2. Jasper's Corner Tap and Kitchen

3.8

Excellent(990)

Price: Moderate

• Southern american • Downtown / Union Square

Booked 1 time today

A long-time local favorite, Jasper’s Corner Tap and Kitchen serves crave-worthy New American cuisine. We feature 18 rotating local craft draft beers in addition to a seasonal lineup of handcrafted cocktails. Our scratch kitchen will delight you with home-style favorites and unique offerings, complemented with unique dishes straight from the imaginations of our talented chefs. Just steps away from famous Union Square in San Francisco and by the Curran Theater, Jasper’s welcomes sports fans, adventurous eaters, movers, shakers, and everyone in-between in an urban-style sophisticated, yet comfortable atmosphere.

3. Level III

3.7

Very Good(398)

Price: Expensive

• Southern american • Downtown / Union Square

Booked 3 times today

Experience social food and modern cocktails at a new level - Level Three. An exciting and sophisticated dining experience inside the JW Marriott San Francisco. This chic restaurant and lounge features a menu of delicious sharable plates crafted from the freshest, local, seasonal ingredients complemented with an extraordinary cocktail menu custom-created by an acclaimed local mixologist. Situated on the third floor lobby level of the hotel highlighted by a 16 story atrium, you can dine on extravagant plates like Dungeness Crab Cake Benedict, Croque Madame, Avocado Toast, "The Burger", Artisinal Grilled Cheese, Filet Mignon, and our Daily Catch!

A photo of House of Prime Rib restaurant

4. House of Prime Rib

4.9

Exceptional(15771)

Price: Very Expensive

• Southern american • Civic Center / Hayes Valley / Van Ness

Booked 281 times today

House of Prime Rib, nestled in the vibrant Civic Center / Hayes Valley / Van Ness neighborhood of San Francisco, is a bastion of exceptional American cuisine, specializing in an unparalleled prime rib experience. Celebrated for its 62-year legacy, this restaurant is a favorite for its "juicy and perfectly cooked" prime rib selections, from the English Cut to the King Henry Cut. Patrons rave about the "tender and flavorful" meat and the classic accompaniments like creamed spinach and Yorkshire pudding, emphasizing that it's not just a meal but an "unforgettable experience." The ambiance, described as energetic and celebratory, perfectly complements the top-notch service and old-school charm, making House of Prime Rib a must-visit for anyone seeking the quintessential American dining experience.

A photo of The Rotunda at Neiman Marcus - San Francisco restaurant

5. The Rotunda at Neiman Marcus - San Francisco

4.8

Exceptional(6019)

Price: Expensive

• Southern american • Downtown / Union Square

Booked 40 times today

The Rotunda at Neiman Marcus in San Francisco's Union Square is a quintessential destination for those seeking an exceptional American dining experience. Known for its elegant ambiance and meticulous service, The Rotunda offers a luxurious afternoon tea service that has won the hearts of locals and tourists alike. Patrons rave about the "delicious assortment of food" and "excellent ambience," highlighting the restaurant's ability to deliver a top-tier culinary experience. From the superb seafood selections like the praised shrimp and crab Louie salad to the classic American burger, every dish is crafted with excellence. Guests continually commend the Rotunda for its "outstanding service" and "beautiful setting," making it a must-visit for anyone looking to indulge in the finest American cuisine in a stunning, historic venue.

6. Wayfare Tavern

4.6

Exceptional(7776)

Price: Moderate

• Southern american • Financial District / Embarcadero

Booked 37 times today

At the heart of San Francisco's bustling Financial District, Wayfare Tavern stands as a beacon of American cuisine, offering a nostalgic yet refined dining experience. Chef Tyler Florence masterfully crafts a menu that captures the essence of early 20th century American fare, earning accolades from diners who rave about the "outstanding" food and service. Known for its moist and flavorful fried chicken and rustic yet elegant setting reminiscent of a Victorian parlor, Wayfare Tavern delivers a unique blend of tradition and innovation. Patrons consistently praise the "perfectly cooked" dishes and the tavern's ability to turn a meal into a cherished memory, making it a cornerstone of the San Francisco dining scene.

A photo of Original Joe's - San Francisco restaurant

7. Original Joe's - San Francisco

4.7

Exceptional(4164)

Price: Moderate

• Southern american • North Beach

Booked 44 times today

Original Joe's in San Francisco's vibrant North Beach is a true emblem of authentic Italian-American cuisine, offering a dining experience that's both classic and exceptional. Established over 80 years ago, it stands as the oldest of the Joe's restaurants nationwide, pioneering the renowned "Joe's Concept." With its iconic red leather booths and a menu celebrated for its Italian American flair, Original Joe's is a bastion of comfort food crafted with a Northern Californian twist. Glowing reviews often highlight dishes like the "best lasagna I have ever tasted" and praise its "incredible customer service." Whether it's the meatballs or the linguini and clams, each dish is a testament to the restaurant's commitment to quality and tradition, making it a must-visit for those seeking a genuine slice of San Francisco's culinary heritage.

A photo of State Bird Provisions restaurant

8. State Bird Provisions

4.8

Exceptional(3212)

Price: Very Expensive

• Southern american • Western Addition

Booked 41 times today

State Bird Provisions in San Francisco's Western Addition neighborhood offers a truly American dining experience that captures both the spirit and innovation of contemporary American cuisine. Renowned for its unique approach, the restaurant features a dim sum-style service that delivers a parade of creative and seasonal dishes, earning high praise from diners. Guests rave about the "extraordinary place with extraordinarily good food" and the "interesting, seasonal, and well-balanced flavors." The energy and creativity of the menu make every visit a delightful adventure, with standouts like the duck liver mousse and the smoked trout dip. The combination of top-notch service and a lively atmosphere ensures a memorable dining experience that epitomizes the best of American culinary excellence. This gem is a proud testament to the rich, evolving food scene of San Francisco.

A photo of Historic John's Grill restaurant

9. Historic John's Grill

4.7

Exceptional(7299)

Price: Expensive

• Southern american • Downtown / Union Square

Booked 27 times today

Nestled in the heart of Downtown San Francisco near Union Square, Historic John's Grill offers an exquisite seafood dining experience that has delighted guests since 1908. Known for its "expertly prepared fresh seafood," this landmark establishment is a favorite among celebrities and locals alike. Diners rave about the "amazing" lobster bisque and the "delicious" broiled halibut, highlighting the freshness and quality of the dishes. With its vibrant atmosphere and a nod to classic San Francisco charm, John's Grill continues to be a top choice for seafood lovers. As one patron put it, "Dinner was outstanding!! I had the broiled halibut which was so fresh and my husband had the Ribeye (also delicious). Our server Daniel was excellent! We will be back!!" Whether you're a local or just visiting, a meal at John's Grill is a must for anyone seeking the best seafood in the city.

10. Top of the Mark

4.3

Awesome(824)

Price: Expensive

• Southern american • Nob Hill

Booked 10 times today

Top of the Mark, perched on the 19th floor in Nob Hill, San Francisco, is a culinary and visual spectacle, making it a must-visit for aficionados of International cuisine. Celebrated as the number 1 hotel bar in California by USAToday, it offers a mesmerizing 360-degree view of the city, including landmarks like the Golden Gate Bridge. Patrons rave about the "over the top desserts" and "tantalizing appetizers" that perfectly pair with innovative cocktails. The live music and vibrant dance scene on Saturdays enhance the dining experience, making every visit memorable. As one reviewer put it, the place is “wow” from the moment you walk in, with food and service that match the breathtaking views. Join us at Top of the Mark for an unforgettable journey through International flavors and San Francisco’s charm.

‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you

N
Nancy
San Francisco Bay Area •2 reviews
5.0
Dined 6 days ago
Celebrated my Dad's 80th Birthday listening to great Live music and eating delicious food! We will definitely be back SOON! Cheers & Love Biscuit & Blues and we will see you soon!
More info
Biscuits and BluesPrice: Expensive• Southern• Downtown / Union Square
•
4.7
E
Erin
San Francisco Bay Area •3 reviews
5.0
Dined on Nov 20, 2024
Prelude is such a gem that we are lucky to have in the Bay Area. In an era where tasting menus can often leave you underwhelmed and needing a slice of pizza at the end, Prelude did the exact opposite. While I did opt for the caviar supplement and added on the sweetbreads dish from the ala carte menu, even without the extras I still would have left full to the brim. Some can’t miss dishes are the stuffed chicken wing, the catfish dumplings, the aforementioned sweetbreads, and the pork chop. The service was warm, friendly, and attentive, and I found the by the glass wine options superb- I was particularly fond of a pour of a very special 1996 Chenin Blanc with dessert. I look forward to returning to Prelude again and again.
More info
PreludePrice: Expensive• Californian• Financial District / Embarcadero
•
4.6
L
Laura
San Francisco Bay Area •1 review
4.0
Dined on Nov 20, 2024
First time at Hard Knox Cafe. We chose it because of the reviews and its proximity to the Legion of Honor. We met my niece and nephew and the staff was very accomodating of guest arriving at different times. The food arrived quickly and was very hot which was terrific. The portions are very generous and we had dinner the next night on the leftovers. The food was flavorful without being spicy. We ordered fried chicken dinner with yam fries and salad; ribs with corn and coleslaw; spicy fried chicken with collard greens and another vegetable; and a pulled pork sandwich with fries. We all enjoyed our food and will definitely be returning.
More info
Hard Knox Cafe on Clement StreetPrice: Moderate• Southern• Richmond District
•
4.8
C
Chadvip
San Francisco Bay Area •7 reviews
5.0
Dined on Nov 7, 2024
Excellent food! Highly recommended. Looking forward to going back.
More info
Hard Knox Cafe on 3rd StreetPrice: Moderate• Southern• Potrero Hill / Dogpatch
•
4.6

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Tenderloin

Southern american

Best Southern American Restaurants in Tenderloin

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148 restaurants available nearby

1. Biscuits and Blues

2. Jasper's Corner Tap and Kitchen

3. Level III

4. House of Prime Rib

5. The Rotunda at Neiman Marcus - San Francisco

6. Wayfare Tavern

7. Original Joe's - San Francisco

8. State Bird Provisions

9. Historic John's Grill

10. Top of the Mark

See what locals rave about

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