Best Cozy Restaurants in Medical Center

50 restaurants available nearby

1. Clementine

4.8

Exceptional(507)

Price: Very Expensive

• Contemporary American • North Central

Booked 24 times today

At Clementine, we’re serving seasonal, innovative eats in a modern & lively atmosphere. Our team, led by John (2023 James Beard nominee for Best Chef: Texas) and Elise Russ, draws inspiration from diverse global flavors. Our ever-evolving menu guarantees fresh and exciting options, while our dishes like the White Mushroom Salad, Ricotta Cavatelli and Clementine Crunch Bar remain cherished favorites. Our beverage menu is small but mighty, carefully curated to include only the most delicious wines & beers from our absolute favorite producers expertly selected to elevate your dining experience. Want your own bottle? Our corkage fee is $35 per 750ml.Our Dining Room provides comfortable indoor seating, while the Kitchen Bar boasts an exciting vantage point overlooking our open kitchen, allowing you to witness the creation of each dish. For a change of scenery, our covered patio, is perfect for al fresco dining, complete with heaters and blankets to keep you cozy on those cool nights.

A photo of Tu Asador - Castle Hills restaurant

2. Tu Asador - Castle Hills

4.7

Exceptional(142)

Price: Expensive

• Mexican • North Central

Booked 18 times today

We're excited to introduce a fresh concept – the "Mexican Steakhouse" – a journey that encapsulates the heart of Mexico's rich flavors. At Tu Asador, we take you on a gastronomic adventure through Northern Mexico's culinary heritage. Our commitment to authenticity ensures that every dish is a genuine representation of flavors passed down through generations.Elevate your dining experience with us – it's not just a meal; it's an Experience. With Tu Asador, you're not just a guest; you're a part of our extended family.

A photo of Luce Ristorante E Enoteca restaurant

3. Luce Ristorante E Enoteca

4.5

Awesome(1202)

Price: Moderate

• Italian • Medical Center

Booked 9 times today

Founded in 2006, Luce is a local favorite featuring many traditional dishes. Flavors which often bring our guests back to their best memories of Italian specialties.My goal for this restaurant to create a warm environment for all guests that is typical of a true Italian heritage. Our menu consists of many Buonincontri family recipes and recipes brought back from travel to Italy. Fresh fish, meats and produce expound throughout Luce's offerings and a focus on the finest ingredients are what make Luce special. House made Gnocchi, Italian rice balls and homemade Mozzarella are just a few examples our passion for the finest Italian food.The word Enoteca means wine library. The walls of the entire restaurant are covered with wine bottles as you would expect books to cover the walls of a library. Wine is a very important part of an experience at Luce, with over 125 choices from our wine list available to you.

A photo of Dean's Steak & Seafood restaurant

4. Dean's Steak & Seafood

4.6

Exceptional(248)

Price: Very Expensive

• Steak • Downtown

Booked 46 times today

Embrace the unique and step into the old school at Dean’s Steak & Seafood. Adapted into a historic 19th-century schoolhouse, this classic steakhouse and bar offers an elevated menu of prime steaks, A5 Japanese and Texas wagyu, and top-quality seafood. Simply put, this one-of-a-kind steakhouse is unlike anything else in the city.If you're looking for an elevated bar experience, visit The Study at Dean's. This intimate speakeasy bar is a cocktail aficionado’s haven, ideal for those who appreciate higher touch ingredients, presentation, and ambiance. Linger over high-end cocktails and small bites in a charming atmosphere with raised banquettes, brass details, and a dedicated outdoor patio shaded under century-old live oak trees - this is the educated choice for a place to connect and unwind.

A photo of Haywire - La Cantera restaurant

5. Haywire - La Cantera

4.4

Awesome(140)

Price: Expensive

• American • La Cantera

Booked 141 times today

Haywire is a Texas-inspired restaurant known for larger-than-life dining experiences, an award-winning wine cellar and extensive list of highly allocated whiskeys. Haywire delivers a true Texas experience through an innovative farm-to-fork menu complete with vendor partners representing every corner of the state.

A photo of Perry's Steakhouse & Grille - San Antonio restaurant

6. Perry's Steakhouse & Grille - San Antonio

4.7

Exceptional(9412)

Price: Expensive

• Steakhouse • La Cantera

Booked 108 times today

Located in La Cantera, Perry’s is a great place to spend an evening in The River City. Our popular Bar 79® presents floor-to-ceiling windows with an optional open-air lounge experience and expansive views overlooking local shops. Plus, the spacious, open design gives you the chance to catch glimpses of the chef as he crafts your favorite dishes — adding to the fresh, familiar atmosphere.

A photo of Ida Claire - San Antonio restaurant

7. Ida Claire - San Antonio

4.6

Exceptional(2509)

Price: Moderate

• Contemporary Southern • Alamo Heights

Booked 124 times today

Ida Claire is a funky, southern influenced restaurant & bar open for breakfast, lunch, and dinner. The food is notched up southern but has influences from different regions. You’ll most likely see dishes you’ve heard of before but with little twists here and there. Our sandwiches will be served on biscuits & we’ll have chicken & waffles on every menu. Brunch is obviously southern & will be a big part of what we do. The drinks are takes on classics like the Mint Julep but revved up & including a lot of house made ingredients.

8. Supper

4.6

Exceptional(3182)

Price: Expensive

• Contemporary American • Downtown

Booked 48 times today

Supper is a cozy restaurant in Downtown San Antonio. Reviewers rave about the 'cozy, restorative vibes', 'warm and fresh aesthetics', and 'unique, inviting and welcoming' ambiance. The restaurant's blend of 'genial South Texas hospitality' and 'American cookery' creates a warm and friendly atmosphere, making it a favorite among locals.

9. Tenfold Rooftop

4.5

Awesome(104)

Price: Expensive

• International • Downtown

Booked 32 times today

One of San Antonio’s most distinguished open-air venues, Tenfold Rooftop has garnered quite the buzz as an upcoming luxury, year-round locale—where every statement it makes packs 10x the punch. The bar’s playful cocktail list highlights tequila and mezcal, offering drinks that range from boozy to frozen to refreshing. Embark on a culinary adventure with Tenfold's exclusive '10x Tour'—a prix fixe menu featuring 10 chef-selected dishes from 10 different regions around the world. This curated experience promises to elevate your dining journey, making it 10x better than the rest.

10. Carriqui

4.8

Exceptional(719)

Price: Expensive

• Unspecified • Downtown

Booked 42 times today

COOKING WITH FIRE, SOUTH TEXAS STYLE Carriqui celebrates the South Texas tradition of drawing flavor from fire. Inspired by the flight path of our namesake bird, our menus feature regional favorites from the Rio Grande Valley, Texas coast, and the Hill Country. Nearly every dish is touched by the glowing embers of our custom-forged pits, smoker, or grill, all fueled by native wood. Along with housemade tortillas, cold margaritas, and warm hospitality, each meal is an opportunity to experience the vibrant food and spirit of our South Texas culture.

‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you

D
David
San Antonio •2 reviews
5.0
Dined 1 day ago
We eat there early evenings based in noise level. Food is amazing and service is always great.
More info
Tu Asador - Castle HillsPrice: Expensive• Mexican• North Central
•
4.7
C
CharlotteVIP
San Antonio •6 reviews
5.0
Dined 2 days ago
The perfect evening for catching up with girlfriends! We had a wonderful time and the food and service was fabulous as always.
More info
ClementinePrice: Very Expensive• Contemporary American• North Central
•
4.8
OT
OpenTable Diner
San Antonio •1 review
5.0
Dined 5 days ago
What can I say, it was our first time and believe me when I say I will return. Drinks were on point, margarita omg delicious, food was a 10 out of 10. Loved the service. It's a must GO!!!
More info
Haywire - La CanteraPrice: Expensive• American• La Cantera
•
4.4
J
Jack
Houston •5 reviews
5.0
Dined on Jan 2, 2025
We had such a great experience the first night of our stay that we cancelled the dinner reservations we scheduled earlier. We travel and eat out often and we love the ambience, the music, the cocktails and the food is over the top. The eggs Benedict for breakfast was excellent. Most of the menu items are handcrafted! We had 4 different servers at 4 different meals and they were all great! They were friendly and very knowledgeable not to mention highly professional. FABULOUS !
More info
Dean's Steak & SeafoodPrice: Very Expensive• Steak• Downtown
•
4.6
L
Lorenzo
San Antonio •3 reviews
5.0
Dined on Dec 14, 2024
Everyone was very nice. The food and drinks were very good.
More info
Luce Ristorante E EnotecaPrice: Moderate• Italian• Medical Center
•
4.5

Explore OpenTable

Medical Center

Best Cozy Restaurants in Medical Center

Price

Cuisine

Regions

Neighborhoods

Top Rated

Dining Options

Seating Options

Accessibility

50 restaurants available nearby

1. Clementine

2. Tu Asador - Castle Hills

3. Luce Ristorante E Enoteca

4. Dean's Steak & Seafood

5. Haywire - La Cantera

6. Perry's Steakhouse & Grille - San Antonio

7. Ida Claire - San Antonio

8. Supper

9. Tenfold Rooftop

10. Carriqui

See what locals rave about

Explore OpenTable