Best Historic Restaurants in Medical Center

21 restaurants available nearby

A photo of Dean's Steak & Seafood restaurant

1. Dean's Steak & Seafood

4.6

Exceptional(177)

Price: Very Expensive

• Steak • Downtown

Booked 40 times today

Embrace the unique and step into the old school at Dean’s Steak & Seafood. Adapted into a historic 19th-century schoolhouse, this classic steakhouse and bar offers an elevated menu of prime steaks, A5 Japanese and Texas wagyu, and top-quality seafood. Simply put, this one-of-a-kind steakhouse is unlike anything else in the city.If you're looking for an elevated bar experience, visit The Study at Dean's. This intimate speakeasy bar is a cocktail aficionado’s haven, ideal for those who appreciate higher touch ingredients, presentation, and ambiance. Linger over high-end cocktails and small bites in a charming atmosphere with raised banquettes, brass details, and a dedicated outdoor patio shaded under century-old live oak trees - this is the educated choice for a place to connect and unwind.

A photo of Boiler House at Pearl restaurant

2. Boiler House at Pearl

4.6

Exceptional(2095)

Price: Expensive

• Contemporary Southern • Downtown

Booked 6 times today

Boiler House at Pearl is a true Texas original. Situated in the historic Pearl Brewery complex on the San Antonio River Walk, this wine-centric restaurant occupies the former “boiler house” which powered the adjacent brewery. Lead by Executive Chef Alberto "Beto" Gutierrez, the menu focuses on grilled items from local farms and markets, with a focus on “Texas ranch-style” cuisine. These delicacies are paired with extraordinary wines from around the world (available by the glass, bottle and “to-go”), full bar, live music and a casual yet energetic atmosphere. The unique list of wines boasts some of the lowest prices in the area.The restaurant incorporates various private dining areas suitable for private or corporate functions and an expansive outdoor patio area where guests can enjoy dining alfresco. We can host groups anywhere from 9 up to 290 guests in our unique, flexible private event spaces.

A photo of Bohanan's Prime Steaks and Seafood restaurant

3. Bohanan's Prime Steaks and Seafood

4.8

Exceptional(8228)

Price: Very Expensive

• Steakhouse • Downtown

Booked 56 times today

Bohanan’s fame is founded on sublimely tender prime beef grilled over fragrant mesquite wood. Enjoy extraordinarily delicious Akaushi beef, Chef/Owner Mark Bohanan’s large custom cuts of prime aged corn-fed beef, succulent seafood flown in fresh daily, and spectacular table-side desserts flambé. Imbibe a classic cocktail at the first-floor Bar at Bohanan’s, then join us upstairs for the best steak you’ve ever eaten. Located in a historic building in downtown San Antonio about a block from the River Walk. AAA Four Diamond rating and Wine Spectator’s Best of Award of Excellence.

A photo of Chart House Restaurant - Tower of the Americas restaurant

4. Chart House Restaurant - Tower of the Americas

4.5

Awesome(16516)

Price: Moderate

• Seafood • Downtown

Booked 192 times today

Chart House is a fine dining restaurant serving seafood & steak and famous for their spectacular views. For more than 50 years, Chart House has redefined the ideal dining experience. With 27 waterfront and showcase locations ranging from the historic to the unforgettable, Chart House restaurants specialize in dazzling views, unique cuisine and exceptional service. From fresh fish specialties to slow-roasted prime rib, the renowned chefs of Chart House have tailored a menu that adds a unique touch to local flavors. And the Chart House happy hour is a guest favorite, where guest favor our signature cocktails and delicious bites you are sure to enjoy. Our original Hot Chocolate Lava Cake is the perfect end to a memorable dining experience at Chart House. Chart House offers the ideal setting for your next event. We would be happy to assist you with all the details of your special occasion.

5. Carriqui

4.8

Exceptional(695)

Price: Moderate

• Unspecified • Downtown

Booked 40 times today

COOKING WITH FIRE, SOUTH TEXAS STYLE Carriqui celebrates the South Texas tradition of drawing flavor from fire. Inspired by the flight path of our namesake bird, our menus feature regional favorites from the Rio Grande Valley, Texas coast, and the Hill Country. Nearly every dish is touched by the glowing embers of our custom-forged pits, smoker, or grill, all fueled by native wood. Along with housemade tortillas, cold margaritas, and warm hospitality, each meal is an opportunity to experience the vibrant food and spirit of our South Texas culture.

A photo of Southerleigh Fine Food & Brewery restaurant

6. Southerleigh Fine Food & Brewery

4.8

Exceptional(3083)

Price: Moderate

• Southern • Downtown

Booked 35 times today

Southerleigh Fine Food & Brewery, helmed by San Antonio Chef Jeff Balfour, brings a modern take on Texas' cross-cultural cuisine to Pearl. Influenced by the coastal classics of Chef Balfour's upbringing in Galveston married with the comfort of southern cuisine, Southerleigh boasts a curated, seasonally shifting menu that reflects Chef Jeff Balfour's innovative craftsmanship. Southerleigh houses a custom-manufactured brewery designed by Portland Kettle Works and brings brewing back to Pearl offering 15 different beers on tap. Southerleigh is located at 136 East Grayson, Suite 120, on the ground floor in the historic Pearl brewhouse.

A photo of Best Quality Daughter restaurant

7. Best Quality Daughter

4.8

Exceptional(475)

Price: Moderate

• Unspecified • Downtown

Booked 72 times today

Best Quality Daughter houses a vibrant, chic décor and new, unique Asian-American menu. In 2018, chef Jennifer Hwa Dobbertin, wanting to address the sparsity of Asian-American female chefs in South Texas, developed a new concept through a series of pop-up dinners called Best Quality Daughter with fellow chef Anne Ng and artist Jennifer Ling Datchuk. Today Best Quality Daughter is located in the historic Mueller House at the Pearl Brewery. Curated by chef Jennifer Hwa Dobbertin, Best Quality Daughter's menu takes inspiration from her travels and the comfort food of her youth as a second-generation Chinese-American.

A photo of Domingo Restaurante restaurant

8. Domingo Restaurante

4.4

Awesome(771)

Price: Expensive

• Mexican / Southwestern • Downtown

Booked 56 times today

Join us in our open-air restaurant on the Historic San Antonio River Walk with a natural ambiance where curated contemporary art intersects with a historical setting. Domingo's menus offer the flavors of South Texas and an agave-forward beverage program celebrating the culture of San Antonio with modern culinary flair.

9. Battalion

4.6

Exceptional(3845)

Price: Moderate

• Italian • Downtown

Booked 17 times today

Located at the "Gateway to Southtown," the Historic and Majestic Firehouse #7 is home to Battalion. After a nearly two year renovation, "The Rock" has been restored as the crown jewel of Southtown. Overlooking the spectacular downtown cityscape and the famous Tower of Americas, Battalion's contemporary design merges perfectly alongside the historic building's strong, yet weathered 1920's craftsmanship. Chef Davis has created an extensive menu of fresh pastas, char-grilled meats, stunning vegetable dishes and Italian classics. Complimenting the menu is a comprehensive wine list and a refreshingly original cocktail program.

10. Bliss Restaurant

4.9

Exceptional(4971)

Price: Very Expensive

• Contemporary American • Downtown

Booked 13 times today

Bliss is consistently among San Antonio’s best restaurants in terms of quality, service and atmosphere. Bliss is located just blocks away from downtown San Antonio in the burgeoning Southtown area. Our mission is to express excellence in the most inclusive, genuine and hospitable way. Bliss serves contemporary American cuisine. Our menu changes frequently with an emphasis on what is seasonal and creative over what is predictable and familiar. Our goal is to create a relaxed yet elegant dining experience in a genuine and comfortable environment.

See what locals rave about

From verified diners like you

V
Vinavip
Houston •19 reviews
5.0
Dined 2 days ago
We always love our dinning experiences at Dean’s Steak House. Whether dinner on a Friday or Saturday evening, or Brunch on the weekend, the food is outstanding, the staff is very welcoming and Friendly. Elegant surroundings and 5 star over all!! Thanks again Victoria, for your hospitality and service to our family on Friday night, with extra care for our 6 months old babygirl :) We also thank you Patrick, for taking such great care of our family at Brunch, outdoors today, with the heater and awesome brunch menu items, along with your friendly attention to detail. We can’t wait to come back soon!!
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Dean's Steak & SeafoodPrice: Very Expensive• Steak• Downtown
•
4.6
T
Ty
San Antonio •3 reviews
5.0
Dined 4 days ago
Great spot for Thanksgiving dinner. The traditional turkey dinner was tops. The cocktails were fantastic too. The Pumpkin Spice Bread Pudding was off the charts. After dinner, a stroll through the Pearl offers nice Christmas decorations that put you in a festive mood. Looking forward to the next visit.
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Boiler House at PearlPrice: Expensive• Contemporary Southern• Downtown
•
4.6
W
Wyatt
San Antonio •1 review
5.0
Dined 4 days ago
Visited on Thanksgiving. Food came out cold. Waiter fixed right away and handles it extremely well. Food tasted really good and I would recommend trying the calamari appetizer. This place is worth it. The experience is amazing. A reservation is a must. Would go back in a heartbeat.
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Chart House Restaurant - Tower of the AmericasPrice: Moderate• Seafood• Downtown
•
4.5
A
Andrew
San Antonio •23 reviews
5.0
Dined 4 days ago
Beautiful renovated old boarding house with south Texas food. Good service and fun.
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CarriquiPrice: Moderate• undefined• Downtown
•
4.8
R
Richellevip
Virginia •7 reviews
5.0
Dined 5 days ago
Our first time dining at Bohanan’s. It truly exceeded expectations. From the moment we were greeted by name walking off the elevator to the very end of the meal, we were made to feel welcome! Food and service were impeccable. Can’t wait to go back.
More info
Bohanan's Prime Steaks and SeafoodPrice: Very Expensive• Steakhouse• Downtown
•
4.8

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Best Historic Restaurants in Medical Center

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21 restaurants available nearby

1. Dean's Steak & Seafood

2. Boiler House at Pearl

3. Bohanan's Prime Steaks and Seafood

4. Chart House Restaurant - Tower of the Americas

5. Carriqui

6. Southerleigh Fine Food & Brewery

7. Best Quality Daughter

8. Domingo Restaurante

9. Battalion

10. Bliss Restaurant

See what locals rave about

Explore OpenTable