129 Best Restaurants Spicy Food in Serra Mesa

129 restaurants available nearby

1. Madison

4.5

Price: Expensive

• Mediterranean • University Heights

Booked 55 times today

With their stunning design, classic cocktails & highly acclaimed fare, Madison finds itself among San Diego's can't miss restaurants! Serving many of Michelin recognized Chef Mario Cassineri classic dishes, perfect for Date Night of celebrating with friends. ʜᴀᴘᴘʏ ʜᴏᴜʀ - ᴇᴠᴇʀʏᴅᴀʏ 4-6ᴘᴍᴛᴜᴇꜱᴅᴀʏ - ʟɪᴠᴇ ᴊᴀᴢᴢ 7-9ᴘᴍᴡᴇᴅɴᴇꜱᴅᴀʏ - ᴅɪɴɴᴇʀ ᴡɪᴛʜ ᴅᴏɢꜱᴛʜᴜʀꜱᴅᴀʏ - ᴅᴊ ꜱᴘɪɴɴɪɴɢ ᴏʟᴅ ꜱᴄʜᴏᴏʟ ᴠɪɴʏʟꜰʀɪᴅᴀʏ & ꜱᴀᴛᴜʀᴅᴀʏ ɴɪɢʜᴛ - ᴀʟᴡᴀʏꜱ ᴀ ᴘᴀʀᴛʏ ᴡᴇᴇᴋᴇɴᴅ ʙᴏᴏᴢʏ ʙʀᴜɴᴄʜ - ʟɪᴠᴇ ᴅᴊꜱꜱᴜɴᴅᴀʏ ɴɪɢʜᴛ - ʟᴀᴛɪɴ ᴊᴀᴢᴢ 6-8ᴘᴍ

A photo of Puesto Mission Valley restaurant

2. Puesto Mission Valley

4.6

Exceptional(2007)

Price: Moderate

• Mexican • Mission Valley

Booked 65 times today

Puesto is family-owned and operated by first generation Mexican American brothers Eric, Alan and Alex Adler, alongside their cousins Isidoro and Moy Lombrozo and founding chef and partner Luisteen Gonzalez. With eight locations in California, Puesto provides an innovative and contemporary approach to authentic Mexican cuisine. Sourcing its ingredients locally and regionally, the restaurant has earned national acclaim for its Mexico City-inspired tacos made with non-GMO organic, heirloom Masienda blue corn stone-ground tortillas, crispy melted cheese and scratch salsas.

A photo of Great Maple San Diego restaurant

3. Great Maple San Diego

4.8

Exceptional(4415)

Price: Moderate

• American • Hillcrest

Booked 51 times today

We Serve Dinner, Lunch, Brunch and Weekday Breakfast. We are a modern American eatery featuring seasonal fare, fresh house made pies, and local produce cocktails. We have a full bar and a social wine list. Open for Outdoor dining!

4. Botanica

4.7

Exceptional(35)

Price: Moderate

• Japanese • North Park

Booked 17 times today

Botanica is a craft cocktail bar offering an exquisite selection of unique cocktails inspired by classic paintings. Our sexy and inviting space is perfect for enjoying artfully crafted drinks paired with delectable small bites. Step into our lounge and experience a fusion of artistic elegance and sophisticated flavors.

A photo of Harmony Cuisine 2B1 restaurant

5. Harmony Cuisine 2B1

4.8

Exceptional(261)

Price: Very Expensive

• Japanese • Kearny Mesa

Booked 17 times today

OpenTable Diners' Choice 2022, 2023 and 2024! Come dine in our modern and relaxing atmosphere, where we serve traditional sushi and unique fusion dishes.Enjoy particularly selected sakes, wines, and unique cocktails that pair exquisitely with our fine dishes. In addition to traditional sushi, and hot and cold Japanese appetizers, our menu includes pastas, homemade desserts, and other regional fusion dishes to cater to a wide range of guests. We are also proud to offer premium A5 Wagyu dishes.Please let us serve you our traditional and creative dishes so that you can enjoy "To Become One (2B1)" with us in Harmony!

6. El Sueño

4.2

Awesome(182)

Price: Moderate

• Mexican • Old Town

Booked 16 times today

Coming Soon to Open Table!Vibrant Mexican Food and Craft Cocktails.

A photo of Alexander's on 30th restaurant

7. Alexander's on 30th

4.7

Exceptional(3107)

Price: Expensive

• Italian • North Park

Booked 80 times today

Neighborhood gem located in the heart of the Historic North Park District, adjoining Balboa Park and the world famous San Diego Zoo. Specializing in homestyle Italian with Gourmet Flair. Hand made Pastas, Award Winning Pizza and Voted Best of Restaurants by San Diego Magazine "Most Romantic". Listed as Top 25 Places to Eat in San Diego "Before You Die" by San Diego Union Tribune. Make memorable celebrations on our beautiful patio, the perfect ambiance for any occasion. Remember to try our diners favorites, The Theodore's Fix Pizza and Baked Vodka Bolognese.Look forward to serving you soon!

A photo of Gravity Heights Mission Valley restaurant

8. Gravity Heights Mission Valley

4.7

Exceptional(214)

Price: Moderate

• American • Mission Valley

Booked 16 times today

We’re not out to take the San Diego beer scene by storm or reinvent the wheel because the truth is, there’s no shortage of good breweries in San Diego. Instead, our aim is to pair that good beer with the same delicious food, exceptional service and genuine hospitality we’re known for so you never have to compromise one for the other again. Situated in Mission Valley, our 9,000 square foot brewpub includes a full service restaurant, an expansive and lush outdoor beer garden, and a pretty stellar team to make sure you always have good food in your mouth and a solid beer in your hand.

A photo of North Italia - Fashion Valley restaurant

9. North Italia - Fashion Valley

4.7

Exceptional(2669)

Price: Expensive

• Italian • Mission Valley

Booked 59 times today

At North, we focus on what we do best: Italian from scratch. Enjoy any of our handmade pastas and pizzas, created with seasonal ingredients and inventive flavors. Or, try a different signature dish, prepared with our fresh flavors from the garden, farm, and sea. We’ve hand crafted seasonal cocktails that pair great with our food, creating a real modern Italia experiences perfect for any occasion.

10. ARLO San Diego

4.2

Awesome(775)

Price: Moderate

• American • Mission Valley

Booked 5 times today

ARLO is an award-winning restaurant known for its scratch-made dishes, crafted from fresh local ingredients. Serving breakfast, weekend DJ brunch, and dinner, ARLO offers a fun and quirky environment. Highlights include a sweeping outdoor patio, swaying palm trees, and a giant outdoor fireplace. The experience is rounded out by an inventive cocktail program, an extensive wine list, and local craft beers on tap. Recently, ARLO won Best Hotel Restaurant and Best Restaurant for Big Groups in the San Diego Magazine Best of 2024 awards. Free parking is available.

Best Restaurants for Spicy Food in Serra Mesa

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Award-winning

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129 restaurants available nearby

1. Madison

2. Puesto Mission Valley

3. Great Maple San Diego

4. Botanica

5. Harmony Cuisine 2B1

6. El Sueño

7. Alexander's on 30th

8. Gravity Heights Mission Valley

9. North Italia - Fashion Valley

10. ARLO San Diego

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