Restaurants near MD Anderson Cancer Center

Price

$$
$$$
$$$$

Cuisine

AmericanItalianSteakhouseSeafoodFrenchIndian

Top Rated

CharmingDog-friendlyFancyGood for business mealsGood for groupsGood for special occasions

Dining Options

All dining options

Delivery only

Takeout only

Seating Options

BarCounterStandardHigh TopOutdoor

Award-winning

James Beard AwardMICHELIN

Accessibility

Gender-neutral restroomWheelchair access

592 restaurants available nearby

How are Featured results ranked

The default order for search results reflects a number of factors, including table availability, restaurant location, search criteria, and restaurant reviews and ratings. In addition, payment made by a restaurant to OpenTable is also a factor for the relative ordering of restaurants.

A photo of Steak 48 - Houston restaurant

1. Steak 48 - Houston

4.9

Exceptional(10407)

$$$$Price: Moderate

• Steakhouse • River Oaks

Booked 179 times today

Steak 48 serves the finest steaks and seafood in an intimate, vibrant setting. Our diverse menu satisfies any craving with the best USDA prime steaks, fresh seafood and shellfish plus inventive and classically inspired sides and appetizers. We can accommodate large groups or provide an intimate setting for a romantic occasion, tailoring your experience. Unique dining nooks provide a different experience each time a guest visits. Visit Steak 48 for the best fine dining experience among the many River Oaks restaurants. Our ambiance is perfect for any occasion, our classic American steakhouse menu features the best steaks in Houston, and you will be impressed by our impeccable service and massive wine and Scotch whiskey list.

A photo of Mexican Sugar Montrose - Regent Square restaurant

2. Mexican Sugar Montrose - Regent Square

4.3

Awesome(248)

$$$$Price: Moderate

• Mexican • Montrose

Booked 136 times today

Mexican Sugar is NOW OPEN at Regent Square in the heart of Montrose! We offer an elevated dining experience that celebrates the vibrancy and richness of Mexico. We take the traditional flavors of Mexican cuisine and elevate them to new heights with our commitment to using only the freshest ingredients and preparing everything from scratch. Our warm and inviting atmosphere inspired by the beauty of Mexican design and architecture provides an ambiance ideal for any dining occasion. From Happy Hour to Lunch, Brunch to Dinner and Late Night, we are so excited to serve you in Montrose!

A photo of Annabelle Brasserie restaurant

3. Annabelle Brasserie

4.5

Awesome(1015)

$$$$Price: Expensive

• French • Montrose

Booked 85 times today

Situated as the anchor restaurant of Autry Park, a 14-acre mixed-use Hanover development on Buffalo Bayou Park, Annabelle Brasserie will serve French cuisine lunch, dinner seven and weekend brunch in a lively atmosphere with picturesque views. To ensure the best experience for all of our guests, we kindly request that outside food or drinks not be brought into the restaurant. We appreciate your cooperation and look forward to serving you!

4. Marmo

4.6

Exceptional(1451)

$$$$Price: Moderate

• Italian • Montrose

Booked 70 times today

Marmo, meaning “Marble” in Italian, will feature fresh hand-rolled pastas, house-made charcuterie, and hand-cut prime steaks. To complement the food menu, Marmo will boast an impressive wine list, with selections from all around the world spotlighted by wines from Italian regions. The bar and lounge will include a baby grand piano where a rotation of Houston’s best singers will perform nightly.Happy Hour is offered daily from 3pm-6pm, on a first-come first-served basis, and is available at our bar, high top tables, and patio. (Please note that we do not accept reservation for our Happy Hour)

A photo of Le Colonial - Houston restaurant

5. Le Colonial - Houston

4.8

Exceptional(3837)

$$$$Price: Expensive

• Vietnamese • Galleria / Uptown

Booked 84 times today

Le Colonial is a celebration of seductive spirit and vivid flavors reminiscent of Saigon in the 1920s. With locations in Atlanta, Chicago, Denver, Delray Beach, Lake Forest, and Naples, the famed Vietnamese restaurant is designed to capture a bygone era of sophistication and opulence. Celebrated restaurateurs Rick Wahlstedt and Joe King deliver exquisite attention to detail in the luxurious, classic, and romantic atmosphere of the River Oaks District. For special occasions, our private dining space provides a bespoke setting for unforgettable celebrations.Business CasualNo athletic wear or athletic attire, including designer athletic line of any kind and model, beach flip flops or any beach attire, tank tops (men), cut-offs, sweatpants, exposed undergarments, and excessively revealing clothing for indoor and outdoor dining. No baseball caps indoors. Seasonal changes may apply.Gratuity will be added to parties of 6 or more. We only allow a maximum of 4 for splitting checks.

6. Uchi Houston

4.8

Exceptional(4513)

$$$$Price: Very Expensive

• Sushi • Montrose

Booked 61 times today

Bringing its hallmark level of quality and service to an urban location, Uchi Houston made its debut in 2012 in the former historic Felix space on Westheimer. Melding culinary innovation with an approachable vibe, the menu features items culled from both Uchi and Uchiko in Austin, along with signature seasonal items created by our Chef team. Reservations are encouraged and can be booked online up to 1 month in advance. Walk-in bar seating is available and is subject to wait times. We look forward to serving you, Kanpai!

7. Coppa Osteria

4.7

Exceptional(589)

$$$$Price: Moderate

• Contemporary Italian • Rice Village

Booked 73 times today

Coppa Osteria is the perfect paring of food and lifestyle, taking its personality from the affluent, family centric West University, Southampton, Rice and Museum District neighborhoods. Its clientele is an eclectic mix of professionals, university academics and young families – who all seem to know one another. With craft cocktails and an extensive wine list, it's easy to find the perfect beverage to pair with Coppa's modern Italian cuisine. Neapolitan-inspired pizzas are some of the most popular items on the menu – the Coppa Pepperoni and Carnissima are crowd favorites. Diners also flock for the Fritto Misto, Burrata Tartufo and Spaghetti Carbonara (Coppa's signature dish). Complete with a lively bar scene and a large outdoor patio that lends itself to sipping rosé and taking in the surrounding neighborhood scenery, Coppa is the ideal setting for an intimate all-day dining with family & friends.For group or private dining for 7+ guests, please submit a private dining inquiry below.

A photo of Guard and Grace - Houston restaurant

8. Guard and Grace - Houston

4.7

Exceptional(1939)

$$$$Price: Expensive

• Steakhouse • Downtown

Booked 82 times today

Named after our daughter Grace, along with the idea that a steakhouse can be graceful, whimsical, and elegant without being dark and moody. What started as a vision to keep the vibe light and airy while letting the outside in, has turned into an Award-winning design of which we couldn't be prouder. This menu is truly meant to offer something for everyone, with often found steakhouse features as well as a plethora of seafood to truly highlight the best of the gulf and beyond. Prime, Dry Aged and local Wagyu cuts of beef in 4 to 40 oz. portions are available to satisfy any sized appetite. Innovative cocktails and wines from around the world top it all off -making Guard and Grace the place to be for happy hour, a couple's night out or your private event. Our family, or Ohana, is a passionate group of culinary obsessives who strive to make memories that will last a lifetime. Houston is a special city that has stolen our hearts, and from the bottom of them, we thank you for joining us.

A photo of Rumi's Kitchen - Houston restaurant

9. Rumi's Kitchen - Houston

4.8

Exceptional(886)

$$$$Price: Expensive

• Persian • Galleria / Uptown

Booked 108 times today

The premier destination for Persian Cuisine in Uptown Houston.

A photo of Mastro's Steakhouse - Houston restaurant

10. Mastro's Steakhouse - Houston

4.8

Exceptional(4142)

$$$$Price: Very Expensive

• Steakhouse • Galleria / Uptown

Booked 88 times today

Mastro's collection of sophisticated, classic Steakhouses and Ocean Club seafood locations are recognized for their combination of world-class service, highly acclaimed cuisine, and live entertainment in an elegant yet energetic atmosphere. A truly unparalleled dining experience.

Dining near MD Anderson Cancer Center at a glance

Updated on 3/1/2025

Maximo

4.9

View restaurant

Discover local gems

Exceptional reviews

Search top-rated restaurants

Contemporary American

Search Contemporary American restaurants

Average check amount

$30 and under

Search in this price range

See what locals rave about

From verified diners like you

T
TerryVIP
Houston •78 reviews
5.0
Dined 2 days ago
Another amazing visit to Le Colonial. The food is incredible. The service by Daniela and team was excellent. The facilities are great. I noticed the restaurant has added a 3% Restaurant Surcharge to the bill. I am not a big fan of this tactic.
More info
Le Colonial - HoustonPrice: Expensive• Vietnamese• Galleria / Uptown
•
4.8
J
JulieVIP
Houston •87 reviews
5.0
Dined 3 days ago
A friend was visiting from out of town so I wanted to take her to Annabelle’s. It’s such a pretty place and I knew that the food would be perfect. Ian took excellent care of us! It was just perfect!
More info
Annabelle BrasseriePrice: Expensive• French• Montrose
•
4.5
S
SandyVIP
Houston •22 reviews
5.0
Dined 3 days ago
I’ll be back. ! Lunch was amazing 🤩 wagu was on point.
More info
MarmoPrice: Moderate• Italian• Montrose
•
4.6
T
Tatiana
Houston •8 reviews
5.0
Dined 3 days ago
Adrian the bartender at the upstairs bar, which is reservation only, was great and very attentive!
More info
Steak 48 - HoustonPrice: Moderate• Steakhouse• River Oaks
•
4.9
OT
OpenTable Diner
Columbus •1 review
5.0
Dined 4 days ago
We went for happy hour and the prices are great for margaritas! They are very flavorful and not too strong
More info
Mexican Sugar Montrose - Regent SquarePrice: Moderate• Mexican• Montrose
•
4.3

Explore OpenTable

Landmark
Neighborhood
City/Region

MarqE Entertainment Center
Domain at CityCentre
Town and Country Village
NRG Astrodome
Highland Park
Edwards Greenway Grand Palace Stadium 2
Katy Mills Shopping Center
Fairfield Inn Texas City
Hotel Sorella CityCentre
Hilton Galveston Island Resort
Galveston Island Convention Center
Willowbrook Shopping Center
Discovery Green
Memorial City Mall
Houston Marriott West Loop by The Galleria
Four Seasons Hotel Houston
Texas Medical Center
Toyota Center
Gibbs Powell House Museum
Magnolia Hotel Houston

W. University / Med Center

Houston