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Best Southern American Restaurants in Mission Bay / South Beach

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145 restaurants available nearby

A photo of House of Prime Rib restaurant
4.8
Exceptional(15754)
Price: Very Expensive
• Southern american • Civic Center / Hayes Valley / Van Ness
Booked 205 times today
House of Prime Rib, nestled in the vibrant Civic Center / Hayes Valley / Van Ness neighborhood of San Francisco, is a bastion of exceptional American cuisine, specializing in an unparalleled prime rib experience. Celebrated for its 62-year legacy, this restaurant is a favorite for its "juicy and perfectly cooked" prime rib selections, from the English Cut to the King Henry Cut. Patrons rave about the "tender and flavorful" meat and the classic accompaniments like creamed spinach and Yorkshire pudding, emphasizing that it's not just a meal but an "unforgettable experience." The ambiance, described as energetic and celebratory, perfectly complements the top-notch service and old-school charm, making House of Prime Rib a must-visit for anyone seeking the quintessential American dining experience.
A photo of Miller & Lux restaurant
4.7
Exceptional(1144)
Price: Very Expensive
• Southern american • Mission Bay / South Beach
Booked 41 times today
Nestled in the vibrant Mission Bay/South Beach neighborhood of San Francisco, Miller & Lux redefines the Contemporary American dining experience. Spearheaded by the renowned Tyler Florence, this modern American Steakhouse delivers an unmatched culinary delight. From the highest-quality steaks sourced from America's finest ranches to a fresh, sustainable seafood selection, each dish is a testament to Tyler's innovative approach to classic American luxury. Patrons rave about the "impeccable service" and "culinary masterpieces," with special mentions of the unique tableside Caesar salad and the meticulously curated wine list. Whether you're there for a "splurge dinner" or celebrating a special occasion, Miller & Lux promises an "outstanding" gastronomic journey that perfectly captures the essence of refined American cuisine.
A photo of The Palm Court at RH San Francisco restaurant
4.7
Exceptional(1731)
Price: Very Expensive
• Southern american • Potrero Hill / Dogpatch
Booked 108 times today
The Palm Court is located in RH San Francisco's Gallery at the Historic Bethlehem Steel Building. Recalling the distinctive glamour of San Francisco's Gilded Age, the stunning statement space is sheathed in Italian Calacatta gold marble and features a cascading center fountain, towering Medjool date palms and glimmering chandeliers. Adjacent to the restaurant, two luminous wine bars offer exceptional wines and Champagnes from around the world.For group dining inquiries, please email: sfhospitality@rh.com
A photo of The Rotunda at Neiman Marcus - San Francisco restaurant
4.8
Exceptional(6006)
Price: Expensive
• Southern american • Downtown / Union Square
Booked 149 times today
The Rotunda at Neiman Marcus in San Francisco's Union Square is a quintessential destination for those seeking an exceptional American dining experience. Known for its elegant ambiance and meticulous service, The Rotunda offers a luxurious afternoon tea service that has won the hearts of locals and tourists alike. Patrons rave about the "delicious assortment of food" and "excellent ambience," highlighting the restaurant's ability to deliver a top-tier culinary experience. From the superb seafood selections like the praised shrimp and crab Louie salad to the classic American burger, every dish is crafted with excellence. Guests continually commend the Rotunda for its "outstanding service" and "beautiful setting," making it a must-visit for anyone looking to indulge in the finest American cuisine in a stunning, historic venue.
A photo of Shelby's Rooftop restaurant
4.4
Awesome(289)
Price: Very Expensive
• Southern american • SOMA
Booked 25 times today
Shelby's Rooftop in the heart of SOMA, San Francisco, epitomizes the quintessential rooftop bar experience with its expertly-crafted cocktails and chic ambiance. Guests rave about the "spectacular views" and the vibrant, "mellow and classy" atmosphere, making it a standout for those seeking a premium bar, lounge, or bottle service venue. Patrons consistently highlight the "delicious" drinks and "great vibes," with special mentions of the mezcal cocktails being "absolutely super savory." The service at Shelby's is commended for being welcoming and attentive, ensuring a memorable visit. Whether you're celebrating a special occasion or just enjoying a casual night out, Shelby's Rooftop offers a breathtaking setting with "top-notch service" and an unmatched urban backdrop, making it a must-visit destination in San Francisco.
A photo of Tartine Manufactory - San Francisco restaurant
4.7
Exceptional(1022)
Price: Expensive
• Southern american • Mission District
Booked 29 times today
Tartine Manufactory in San Francisco's vibrant Mission District is hailed as a haven for pizza aficionados, offering a delightful culinary experience with its world-class sourdough pizzas. Renowned for its market-driven menu that showcases the artisanal bread-making prowess of Chad Robertson, the restaurant earns rave reviews for its unique offerings. Guests consistently praise the "delicious" and "creative" pizza options, like the seasonal corn pizza which has been described as "spectacular." The inviting atmosphere complements the exceptional food, with one review noting, "The service, environment, and food were incredible." Whether it's the cacio e pepe pizza enhanced with fresh arugula or the burrata peach salad, each dish is crafted with the utmost care, making Tartine Manufactory a must-visit for those seeking authentic and high-quality Pizzeria cuisine in San Francisco.
A photo of State Bird Provisions restaurant
4.8
Exceptional(3203)
Price: Very Expensive
• Southern american • Western Addition
Booked 84 times today
State Bird Provisions in San Francisco's Western Addition neighborhood offers a truly American dining experience that captures both the spirit and innovation of contemporary American cuisine. Renowned for its unique approach, the restaurant features a dim sum-style service that delivers a parade of creative and seasonal dishes, earning high praise from diners. Guests rave about the "extraordinary place with extraordinarily good food" and the "interesting, seasonal, and well-balanced flavors." The energy and creativity of the menu make every visit a delightful adventure, with standouts like the duck liver mousse and the smoked trout dip. The combination of top-notch service and a lively atmosphere ensures a memorable dining experience that epitomizes the best of American culinary excellence. This gem is a proud testament to the rich, evolving food scene of San Francisco.
A photo of Wayfare Tavern restaurant
4.6
Exceptional(7764)
Price: Moderate
• Southern american • Financial District / Embarcadero
Booked 117 times today
At the heart of San Francisco's bustling Financial District, Wayfare Tavern stands as a beacon of American cuisine, offering a nostalgic yet refined dining experience. Chef Tyler Florence masterfully crafts a menu that captures the essence of early 20th century American fare, earning accolades from diners who rave about the "outstanding" food and service. Known for its moist and flavorful fried chicken and rustic yet elegant setting reminiscent of a Victorian parlor, Wayfare Tavern delivers a unique blend of tradition and innovation. Patrons consistently praise the "perfectly cooked" dishes and the tavern's ability to turn a meal into a cherished memory, making it a cornerstone of the San Francisco dining scene.
A photo of Angler San Francisco restaurant
4.7
Exceptional(224)
Price: Very Expensive
• Southern american • Financial District / Embarcadero
Booked 38 times today
Angler San Francisco, a Michelin-starred gem nestled on the Embarcadero waterfront, offers an unparalleled seafood experience that is both authentic and innovative. With a focus on the freshest ingredients sourced from Northern California, Angler celebrates the natural flavors of the sea, enhanced by the primal touch of their wood burning hearth. Diners rave about the quality and creativity of the dishes, describing them as "spectacular" and "sublime," with special mentions of the perfectly cooked fish and inventive seafood sauces. The ambiance and views complement the culinary journey, making every visit to Angler a memorable feast of the senses. Whether you opt for the praised tasting menu or the exceptional 'Let Us Cook For You' option, Angler promises an extraordinary dining experience right in the heart of San Francisco's Financial District.
A photo of Boulevard restaurant
4.7
Exceptional(9041)
Price: Very Expensive
• Southern american • Financial District / Embarcadero
Booked 61 times today
Boulevard, nestled in the vibrant Financial District/Embarcadero area of San Francisco, epitomizes the essence of Contemporary American cuisine with an innovative twist. The restaurant recently refreshed its approach, offering a multi-course prefix menu that dazzles diners. Reviewers rave about its culinary delights, describing dishes like the "out of this world" strawberry yuzu sundae and flavor-packed stuffed morels as highlights of their dining experience. Boulevard's commitment to quality is evident, with one patron noting, "Boulevard never disappoints! Excellent food. We have eaten there many times and it is always exceptional." This gem provides not just a meal but a memorable dining adventure, making it a must-visit for those seeking exceptional Contemporary American fare in a sophisticated setting.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Erin
    San Francisco Bay Area •3 reviews
    5.0
    Dined 3 days ago
    Prelude is such a gem that we are lucky to have in the Bay Area. In an era where tasting menus can often leave you underwhelmed and needing a slice of pizza at the end, Prelude did the exact opposite. While I did opt for the caviar supplement and added on the sweetbreads dish from the ala carte menu, even without the extras I still would have left full to the brim. Some can’t miss dishes are the stuffed chicken wing, the catfish dumplings, the aforementioned sweetbreads, and the pork chop. The service was warm, friendly, and attentive, and I found the by the glass wine options superb- I was particularly fond of a pour of a very special 1996 Chenin Blanc with dessert. I look forward to returning to Prelude again and again.
    More info
    PreludePrice: Expensive• Californian• Financial District / Embarcadero
    4.6
  • Laura
    San Francisco Bay Area •1 review
    4.0
    Dined 3 days ago
    First time at Hard Knox Cafe. We chose it because of the reviews and its proximity to the Legion of Honor. We met my niece and nephew and the staff was very accomodating of guest arriving at different times. The food arrived quickly and was very hot which was terrific. The portions are very generous and we had dinner the next night on the leftovers. The food was flavorful without being spicy. We ordered fried chicken dinner with yam fries and salad; ribs with corn and coleslaw; spicy fried chicken with collard greens and another vegetable; and a pulled pork sandwich with fries. We all enjoyed our food and will definitely be returning.
    More info
    Hard Knox Cafe on Clement StreetPrice: Moderate• Southern• Richmond District
    4.8
  • John
    San Francisco Bay Area •3 reviews
    5.0
    Dined on Nov 14, 2024
    Nice blues club (really a night club) that serves southern styled food. Go for the music
    More info
    Biscuits and BluesPrice: Expensive• Southern• Downtown / Union Square
    4.7
  • Chadvip
    San Francisco Bay Area •7 reviews
    5.0
    Dined on Nov 7, 2024
    Excellent food! Highly recommended. Looking forward to going back.
    More info
    Hard Knox Cafe on 3rd StreetPrice: Moderate• Southern• Potrero Hill / Dogpatch
    4.6
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