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Sassafras Southern Bistro, Greenville, SC

Sassafras Southern Bistro

4.9
4.9
3483 Reviews
$30 and under
Southern

Make a reservation

2 people
7:00 PM

Select a time

  • Good for special occasions
  • Charming
  • Neighborhood gem
Located in the heart of downtown Greenville, South Carolina, Sassafras Southern Bistro serves an eclectic menu of American cuisine with a truly Southern influence. Menu items include steak, fresh seafood, salads, and amazing desserts. Sassafras Southern Bistro has a full bar featuring local beers on tap and an extensive wine selection both by the glass and by the bottle.



Start out your meal at Sassafras Southern Bistro with one of their amazing appetizers like the spicy pork tenderloin or the famous blue crab and pepper-jack nachos. Choose from entrees like the raved about shrimp and grits or the filet with house made pimento. Some vegetarian and gluten free options are available upon request.

Additional information

  • Dining style
    Casual Dining
  • Price
    $30 and under
  • Cuisines
    Southern, American
  • Hours of operation
    Mon–Thu 5:00 pm–9:00 pm Fri 5:00 pm–9:30 pm Sat 4:30 pm–9:30 pm
  • Phone number
    (864) 235-5670
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Dress code
    Casual Dress
  • Neighborhood
    Greenville
  • Cross street
    Main Street and Coffee Street
  • Parking details
    Parking is available in the Richardson Street parking garage that is conveniently located just a few steps away and is free to park on the weekends!
  • Public transit
    Parking garage is located at 66 Richardson Street. Once you park your car walk out of the parking garage and walk right into the open area. You will see Sassafras here, we have the green awning!
  • Additional
    Bar/Lounge, Beer, BYO Wine, Cocktails, Corkage Fee, Full Bar, Gluten-free Options, Happy Hour, Non-Smoking, Patio/Outdoor Dining, Patio/Outdoor Dining, Private Room, Wheelchair Access, Wine

What 3,483 people are saying

Overall ratings and reviews

Reviews can only be made by diners who have eaten at this restaurant

4.9
4.9 based on recent ratings
  • 4.8Food
  • 4.9Service
  • 4.8Ambience
  • 4.8Value

NoiseModerate

Loved For

  • South Carolina

    Best Overall

  • South Carolina

    Best Value

  • South Carolina

    Southern

  • Greenville

    Best Overall

  • Greenville

    Best Food

  • Greenville

    Best Service

  • Greenville

    Best Ambiance

  • Greenville

    Best Value

  • Greenville

    Good for groups

  • Greenville

    Great for outdoor dining

Review summary

AI-generated from verified diner reviews
Sassafras Southern Bistro is highly praised for its "amazing food," "excellent service," and "beautiful ambiance." Guests enjoy generous portions and a varied Southern menu, featuring standout dishes like pecan-crusted trout and seafood trio. The staff, including attentive servers and a friendly owner, ensure every visit is "a great dining experience."
3,483 Reviews
  1. Champ

    VIP

    East Texas

    33 reviews

    5.0

    33 reviews

    Dined 1 day ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    We eat here every trip to Greenville! Fab menu and really good healthy options! Lovely place!

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  2. LaurieE

    Philadelphia

    9 reviews

    5.0

    9 reviews

    Dined 3 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Great dinner (as always). One of our top dinner places

    Is this helpful?

  3. Brian

    VIP

    Tampa

    7 reviews

    5.0

    7 reviews

    Dined 4 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 4
    The food and service were great! Taylor did an awesome job, and her recommendation on the scallops was spot on! It was a wonderful dish, as was the shrimp and grits. We would definitely go back! Great location as well.

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  4. AlyssaG

    Charleston

    2 reviews

    5.0

    2 reviews

    Dined 4 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Great spot for date night or celebrating a special occasion! This visit my husband and I enjoyed the crispy shrimp appetizer (think better version of bang bang shrimp) which was delicious. For entrees we got the Mahi + crab meat and the wasabi tuna. Brussels sprouts were our favorite side! They make a classic old fashioned that’s always a solid choice. Great atmosphere and service as always! We will be back again.

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  5. Sandra

    VIP

    Chicago

    11 reviews

    5.0

    11 reviews

    Dined 4 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Shirley & Rachel, our servers were amazing. Food was great!

    Is this helpful?

  6. Roshell

    Norfolk/Suffolk

    5 reviews

    5.0

    5 reviews

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    So enjoyed this restaurant! The building was beautiful, the employees definitely were kind and our server (sorry can't remember here name for sure, she was a older caucasian woman with blonde hair in a cute short cut and she wore glasses). She was so sweet...she definitely gave us some of the best Southern Hospitality! We each got something different to eat, but all the meals were amazing!!! They had this appetizer that was made of homemade potato chips, tender steak, gorginzola, and yummy cheese sauce. I believe they called the app Steak and Gorginzola Nachos. We thought it sounded good, so we ordered it and we were not disappointed, so glad we got it!!! They must be popular because after we got them I noticed 3 other tables around them got them as well. Long story short, wonderful place...if you are ever in the area, give your taste buds a treat and go there!!!

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  7. SusanD

    Raleigh

    3 reviews

    5.0

    3 reviews

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 4
    Walked in and was immediately greeted, seated (we did have a reservation) and acknowledged by our waitress. My husband ordered the seafood trio and I had the shrimp and grits. Both were delicious! This will not be our last visit to Sassafras- Southern Bistro!

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  8. Sandra

    Richmond

    70 reviews

    5.0

    70 reviews

    Dined 7 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Great good, varied menu, interesting building, wonderful service. Isacc was our waiter and provided excellent service. Only complaint would be to have cushions for the seats on the patio. We had to sit on our coats to be comfortable. Might want to invest in a few cushions anyhow. Other than that GREAT dinner and evening.

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  9. Joseph

    Charleston

    3 reviews

    5.0

    3 reviews

    Dined on February 25, 2025

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Always a great experience and consistently excellent food. Everyone in our party raved about the food and the wonderful atmosphere.

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  10. John

    VIP

    Charleston

    28 reviews

    5.0

    28 reviews

    Dined on February 25, 2025

    1. Overall 5
    2. Food 4
    3. Service 5
    4. Ambience 4
    Great food, service, and location. All of our entrees were very good.

    Is this helpful?

FAQs

Sassafras Southern Bistro is rated 4.9 stars by 3483 OpenTable diners.

Yes, you can generally book this restaurant by choosing the date, time and party size on OpenTable.

Make a reservation

2 people
7:00 PM

Select a time

Google Map for Sassafras Southern Bistro

103 N Main St #107, Greenville, SC 29601

Additional information

  • Cross street
    Main Street and Coffee Street
  • Neighborhood
    Greenville
  • Hours of operation
    Mon–Thu 5:00 pm–9:00 pm Fri 5:00 pm–9:30 pm Sat 4:30 pm–9:30 pm
  • Price
    $30 and under
  • Cuisines
    Southern, American
  • Dining style
    Casual Dining
  • Dress code
    Casual Dress
  • Parking details
    Parking is available in the Richardson Street parking garage that is conveniently located just a few steps away and is free to park on the weekends!
  • Public transit
    Parking garage is located at 66 Richardson Street. Once you park your car walk out of the parking garage and walk right into the open area. You will see Sassafras here, we have the green awning!
  • Payment options
    AMEX, Discover, Mastercard, Visa
  • Additional
    Bar/Lounge, Beer, BYO Wine, Cocktails, Corkage Fee, Full Bar, Gluten-free Options, Happy Hour, Non-Smoking, Patio/Outdoor Dining, Patio/Outdoor Dining, Private Room, Wheelchair Access, Wine
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