Diners' Choice: American restaurants in Mississippi

OpenTable

Updated December 05, 2024

Looking for restaurants with the best overall American cuisine in Mississippi? You’re in the right place. Each month OpenTable analyzes more than 400,000 new diner reviews. We sort the results by category to help you discover new favorites. It's a great partnership: you reserve, eat, and review. We listen...and deliver the results for all to benefit. Enjoy!

Restaurant Anchuca

4.9

4.9 (38)

$31 to $50

American

Vicksburg

About the restaurant

Nestled within Vicksburg’s oldest neighborhood, & located inside the town’s oldest columned mansion/bed & breakfast that survived the Civil War, Restaurant Anchuca exudes true Southern hospitality & happiness — after all, the name “Anchuca” is derived from the Choctaw word meaning “happy home.”

Don’t miss the filet — it’s so tender you won’t need a steak knife! Guests consistently say it’s the best filet they’ve ever had. Other specialties include the scrumptious shrimp & grits, paneed catfish featuring Mississippi farm-raised catfish, exceptional chicken piccata, & a variety of dinner and dessert specials.

Looking for great wine? With an emphasis on family-owned vineyards, artisan producers, highly sought after imports, & a wide range of price points, Restaurant Anchuca is proud to deliver world-class wine alongside Mississippi’s world-class hospitality. Our award-winning selection has been curated especially for Restaurant Anchuca by Mississippi’s only advanced-level sommelier.

Top review

Annette

Dined on Dec 5, 2024

Anchuca is hands down our favorite place to have dinner in Vicksburg. From the elegant atmosphere to the great customer service and fantastic food, every detail contributes to a memorable night! Keep doing what you are doing !!!!

Phillip M's

4.7

4.7 (517)

$31 to $50

American

Philadelphia

About the restaurant

Phillip M’s is considered the best fine dining restaurant in the South, receiving Wine Spectator’s “Award of Excellence" in 2022 & 2023. Phillip M’s, named in honor of the late Tribal Chief Phillip Martin, received 2014’s Best of Southern Gaming Awards for Best Restaurant.

In addition to its award-winning wines, Phillip M’s offers a brand-new menu featuring everything from fine steaks, fresh seafood, and extraordinary wines to decadent desserts. Signature dishes include 16oz. Bone in Ribeye and Shrimp and Salmon.

Top review

Michael

Dined on Nov 28, 2024

We appreciated that the restaurant was open on Thanksgiving. We enjoyed everything but prime rib was a bit on the salty side. Overall, a good experience.

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4.8

4.8 (381)

$30 and under

American

Ocean Springs

About the restaurant

* Voted BEST DATE NIGHT SPOT
*We are lively and energetic! Opt for outdoors for a quieter experience!
*Reservations required for dinner only.
* Parties of 12 guests or larger are only done via phone.
*Lunch reservations for groups of 6 or more only.

Maison de Lu was started in Ocean Springs in 2008. A small sandwich shop evolved into a town staple! Offering different menus for lunch and dinner allows appeal to anyone! We offer a beautiful courtyard dining experience (with heaters), a full service bar, and a lively indoor dining. Whether it's date night with that special someone or girl's night, we've got you covered!

Our lunch menu features unique salads, creative sandwiches, and fresh local seafood. Our dinner menu opens up to anything from steak to seafood! We are known for fresh fish, and specialty meats such as our New Zealand Lamb, veal chop, and brined pork chop! We encourage people to "get outside the box" when dining with us!

Top review

Tammy

Dined 4 days ago

Always my Fav downtown! Ryan and his team have taken MDL to a different level!

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4.8

4.8 (510)

$31 to $50

American

Tupelo

About the restaurant

Recently named the Best Fining Dining Restaurant in Mississippi by Mississippi Magazine and located in the Fairpark District, Park Heights offers Chef Thomas Lester's menu including seared hanger steak, yellowfin tuna tartar, heirloom tomato caprese, prosciutto wrapped monkfish and prime cuts of beef. The main dining room, with its reclaimed hardwood floors and retro lighting, provides an atmosphere that is sophisticated without feeling formal. Often sited as the best in town, the service is professional and gracious, and the wine list is extensive. If you enjoy dining al fresco, try the rooftop or patio which have amazing views of downtown.

Top review

DebraVIP

Dined on Dec 7, 2024

This is our favorite restaurant in Tupelo. Food is always delicious and the service is excellent. The restaurant is comfortable and lovely. We brought out of state guests here tonight and everyone enjoyed their meal. I had the Springer brick chicken, which was juicy and very good. My husband had the pork chop and loved it. We tried the fried apple pie for dessert- it's three small fried apple pies dusted with powdered sugar and served with a sauce. It's a bit too sweet for me but I found if I avoided the sauce, the apple pie was good. My husband ate all three of his apple pies plus one of mine so it obviously wasn't too sweet for him!

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Popular dish

Miso BBQ Salmon

McEwens - Oxford

4.8

4.8 (1184)

$30 and under

American

Oxford

About the restaurant

McEwen's Oxford is passionate about food, wine, and you! We strive to create a place you long to come back to again and again. With an eclectic blend of styles, McEwen's Oxford emphasizes Southern food that is raised to new and unusual heights. Lunch offers a wide array of excellent sandwiches, salads and business entrees, while dinner leans toward the more elaborate and inventive. Our commitment to a relaxed atmosphere and charming personality has McEwen's destined to become one of Oxford's most popular destinations. We boast on employing a knowledgeable and attentive staff that is always ready to serve our guests. In addition to the bar and dining room, a private room is available for parties up to 25 people.

Top review

judyVIP

Dined 4 days ago

We had out of town friends come to Oxford for lunch. Everyone enjoyed their food, service was great and the atmosphere was nice Great time!

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Popular dish

Duck Gumbo

Patio 44- Biloxi

4.5

4.5 (763)

$30 and under

American

Biloxi

About the restaurant

Patio 44 opened their gates to the Pine Belt in September 2013, and expanded to the Mississippi Gulf Coast in November 2016, offering an experience like no other. Our beautiful patio-themed restaurant not only provides the area with a beautiful 50 seat patio, but also a very elegant indoor dining area and private area. Patio 44 offers a Chef-driven menu that uses only the finest ingredients possible, a wine list that offers more than 100 bottles from across the world, and one-of-a-kind Hand Crafted Cocktails. Come see what we have to offer. Casual dining at its best!

Top review

DeniseVIP

Dined 7 days ago

Great food and good service. We sat at the bar, but Micah was a great server and had some delicious suggestions. He also went out of the way to make sure our delayed appetizers were expedited and still hot! All the staff was focused on satisfying us from the hostesses until we left. We (3 sisters) were in town for the marathon and really appreciated the service and terrific food.

Patio 44-Gulfport

4.4

4.4 (408)

$30 and under

American

Gulfport

About the restaurant

Polished casual dining serving the finest coastal seafood and steaks on the Mississippi Gulf Coast. Featuring the regions best selection of premium wines and spirits. Relaxed ambiance with a scenic view from our patio of the Gulfport Harbor and Jones Park.

Top review

Pamela

Dined 7 days ago

Patio 44 in Gulfport MS was a great experience… from the service to the food.. very fulfilling! I will return.

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Popular dish

Filet

One Thirty One Lameuse

4.2

4.2 (215)

$31 to $50

American

Biloxi

About the restaurant

Welcome to One Thirty One Lameuse, the newest restaurant in downtown Biloxi! We invite you to explore and be inspired by our restaurant while allowing us to help you host your perfect event. We are open Wednesday - Sunday.

Top review

stacey

Dined 6 days ago

We had a fabulous meal here, everything was above and beyond. Food was outstanding, great variety and interesting delicious dishes, cocktails and wine were great. And last but not least the service was top notch. Definitely give them a try you will not be disappointed!

Hard Rock Cafe - Biloxi

4.4

4.4 (497)

$30 and under

American

Biloxi

About the restaurant

Hard Rock Cafe is a global phenomenon with 185 cafes that are visited by nearly 80 million guests each year. The first Hard Rock Cafe opened on June 14, 1971, in London, England, and from there the brand has expanded to major cities and exotic locations around the world.

Top review

Kathleen

Dined 2 days ago

It was great food! Our waitress was unbelievable! She was fantastic!

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Experience

Celebrate Together this Holiday Season

Experience

Celebrate Christmas Day with Us!

Experience

New Year's Eve Celebration

Taste Bar & Grill

4.3

4.3 (15)

$31 to $50

American

Jackson

About the restaurant

Nestled in the heart of Jackson, Taste Bar + Grill is more than just a cigar bar, lounge, and restaurant – it's an experience. Whether you're seeking a moment of relaxation with a fine cigar, a lively evening with friends, or a memorable dining experience accompanied by live music, our venue promises to exceed your expectations.

Indulge your senses in our restaurant, where every dish is a masterpiece. Our menu blends contemporary flair with timeless favorites, using locally sourced ingredients to create dishes that delight both the palate and the soul. Whether you're here for a leisurely lunch, a romantic dinner, or a celebratory feast, our chefs are dedicated to delivering an unforgettable culinary experience.

Top review

LaDonna

Dined 4 days ago

This experience was phenomenal from the ambiance, food and drinks! I would highly recommend! Lovely Aesthetics!

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